Hmmm. Have you activated V2 already? I think if you type "activate2" in the Windows search bar, it should pop up. Although I don't think deactivated voicebanks should cause it to be unable to open. You might try uninstalling and reinstalling. Make sure you let it do a "complete" install, instead of custom. (At least for the first time. If you ever buy any more Vocaloid2 voicebanks, you can do a custom install and only install the voice database)